The Occupational Opportunist: an Update on Erysipelothrix rhusiopathiae Infection, Disease Pathogenesis, and Microbiology

摘要: Abstract The genus Erysipelothrix currently consists of four named species, the most clinically significant which is E. rhusiopathiae. rhusiopathiae found ubiquitously in environment, with worldwide prevalence. organism identified as both a pathogen and saprophyte for diverse hosts, ranging from fish amphibians to birds, mammals, insects. recognized etiological agent swine erysipelas, disease economic consequence. Human clinical infections are generally result occupational zoonotic exposure infected animal tissues or by-products. Although rare, three distinct forms human recognized: localized cutaneous cellulitis (human erysipeloid), disseminated infection, an infectious endocarditis that usually secondary sepsis. Diagnosis infection can be complicated, particularly limited history; therefore, microbe may under-recognized. From laboratory perspective, diagnostic challenges include bacterium's Gram stain variability variable cellular colony morphologies occur during identification. While treatable routine antimicrobials, empiric therapeutic interventions hampered due intrinsic vancomycin resistance. recent availability genome will strengthen our understanding organism's pathogenesis expand knowledge about spectrum infections.