Time-kill studies of tea tree oils on clinical isolates

摘要: Tea tree oil has recently emerged as an effective topical antimicrobial agent active against a wide range of organisms. may have clinical application in both the hospital and community, especially for clearance methicillin-resistant Staphylococcus aureus (MRSA) carriage or hand disinfectant to prevent cross-infection with Gram-positive Gramnegative epidemic Our study, based on time-kill approach, determined kill rate tea several multidrug-resistant organisms, including MRSA, glycopeptide-resistant enterococci, aminoglycoside-resistant klebsiellae, Pseudomonas aeruginosa Stenotrophomonas maltophilia, also sensitive microorganisms. The study was performed two chemically different oils. One standard other Clone 88 extracted from specially bred tree, which been selected increased activity decreased skin irritation. results confirm that cloned had when compared oil. Most indicated susceptibility pattern Gram reaction organism did not influence rate. A rapid killing time (less than 60 min) achieved oils most isolates, but MRSA killed more slowly