Treatment of severe ocular surface disorders with albumin eye drops.

作者: Marc Schargus , Markus Kohlhaas , Jan Darius Unterlauft

DOI: 10.1089/JOP.2014.0161

关键词:

摘要: Abstract Purpose: Promising healing effects by albumin eye drops (AED) on the corneal epithelium have been demonstrated. The aim of this study was to analyze retrospectively if AED are an effective treatment for severe ocular surface defects and recurrences can be reduced. Methods: Seventeen patients with persistent epithelial (PED) 30 sterile ulcers (CU) were treated either 5% or 0.1% hyaluronan (HED) 8 times daily until complete closure. Sizes defects, length follow-up period, as well recurrence rate evaluated. Follow-up PED carried out 126±21 days in group 142±39 HED group. For CU cases, regular visits performed 117±15 112±28 Results: Nine 11±4 (8 patients) 10±3 closed, on...

参考文章(28)
G. Geerling, D. Hartwig, Autologe Serum-Augentropfen zur Therapie der Augenoberfläche Der Ophthalmologe. ,vol. 99, pp. 949- 959 ,(2002) , 10.1007/S00347-002-0661-6
Ian A. Cree, Ian A. Cree, John K. G. Dart, John K. G. Dart, Peng T. Khaw, Peng T. Khaw, Julie T. Daniels, Gerd Geerling, Gerd Geerling, Toxicity of Natural Tear Substitutes in a Fully Defined Culture Model of Human Corneal Epithelial Cells Investigative Ophthalmology & Visual Science. ,vol. 42, pp. 948- 956 ,(2001)
K. Kasper, C Kremling, G. Geerling, Toxizität neuer Benetzungs- und Konservierungsmittel in vitro Ophthalmologe. ,vol. 105, pp. 557- 562 ,(2008) , 10.1007/S00347-007-1640-8
Nikolaos G Ziakas, Konstantinos G Boboridis, Chryssa Terzidou, Tatiana L Naoumidi, Dimitris Mikropoulos, Eirini N Georgiadou, Nick S Georgiadis, Long-term follow up of autologous serum treatment for recurrent corneal erosions. Clinical and Experimental Ophthalmology. ,vol. 38, pp. 683- 687 ,(2010) , 10.1111/J.1442-9071.2010.02304.X
G. Geerling, F. Grus, B. Seitz, D. Hartwig, F. Schirra, Arzneimittelrechtliche Erlaubnis bei der Herstellung von Serum-Augentropfen Ophthalmologe. ,vol. 105, pp. 632- 638 ,(2008) , 10.1007/S00347-008-1751-X
G Geerling, Autologous serum eye drops for ocular surface disorders British Journal of Ophthalmology. ,vol. 88, pp. 1467- 1474 ,(2004) , 10.1136/BJO.2004.044347
G. Geerling, J.D. Unterlauft, K. Kasper, S. Schrader, A. Opitz, D. Hartwig, Eigenserum und alternative Blutprodukte zur Behandlung von Augenoberflächenerkrankungen Ophthalmologe. ,vol. 105, pp. 623- 631 ,(2008) , 10.1007/S00347-008-1750-Y
Renate Ferreira de Souza, Friedrich E. Kruse, Berthold Seitz, Autologes Serum bei sonst therapieresistenten Hornhautepitheldefekten - Prospektive Studie an den ersten 70 Augen Klinische Monatsblatter Fur Augenheilkunde. ,vol. 218, pp. 720- 726 ,(2001) , 10.1055/S-2001-18663
K. Tsubota, E. Goto, H. Fujita, M. Ono, H. Inoue, I. Saito, S. Shimmura, Treatment of dry eye by autologous serum application in Sjögren's syndrome British Journal of Ophthalmology. ,vol. 83, pp. 390- 395 ,(1999) , 10.1136/BJO.83.4.390