Intrauterine insemination with frozen sperm increases pregnancy rates in donor insemination cycles under gonadotropin stimulation

摘要: Objective To compare the efficacy of IUI donor and pericervical insemination in frozen sperm cycles under gonadotropin stimulation. Design Couples where infertility was caused by male conditions were randomized into two groups: insemination. Semen samples, stimulation, ovarian monitoring same both groups. One performed per cycle as against inseminations. Setting The program at Human Reproduction Unit Hospital Cruces, Pais Vasco University. Patients Eighty-eight women (47 41 insemination) with least one patent fallopian tube Main Outcome Measure Intrauterine gestational sac observed transvaginal ultrasound. Results Per woman pregnancy rate (PR) higher than (65.96% versus 41.46%, odds ratio [OR] = 2.73, confidence interval [CI] 1.06 to 7.2). Pregnancy rates always irrespective husband's status, but statistical significance not reached any subgroups analyzed independently. PR also significantly insemination: 24.03% (31/129) 11.89% (17/143) (OR 2.34, CI=1.17 4.71). Moreover, cumulative (86% 49.5%) 6, CI=1.98 18.80). Conclusion PRs IUI.