Extended-spectrum and metallo-beta-lactamases among ceftazidime-resistant Pseudomonas aeruginosa in Riyadh, Saudi Arabia.
作者： Mohamed H Al-Agamy , Atef M Shibl , Abdulkader F Tawfik , Noura A Elkhizzi , David M Livermore
DOI: 10.1179/1120009X12Z.00000000015
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摘要: We investigated the extended-spectrum (ESBLs) and metallo-beta-lactamases (MBLs) among Pseudomonas aeruginosa isolates in Saudi Arabia. Disc susceptibility testing was performed on 200 P. collected during 2010 at Armed Forces Hospital Riyadh, with MIC phenotypic screening for ESBLs MBLs carried out those found to be ceftazidime resistant. Genes were sought by PCR. Thirty-nine (19·5%) resistant, mostly considerable resistance other antibiotics except colistin. Twenty-three of these 39 (59%) appeared ESBL positive 16 (41%) had MBLs. blaVEB, blaGES genes 20 (86·95%), 5 (21·74%) 23 ESBL-positive isolates, respectively whilst blaVIM detected all MBL-producers. blaOXA-10-like often accompanied or blaGES. Several similar antibiogram β-lactamase profiles, may represent outbreaks; nevertheless, collection not dominated by...
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sci-hub.se 参考文章(21)
Mary Jane. Ferraro, Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically NCCLS. ,(2000)
Xiaofei Jiang, Zhe Zhang, Min Li, Danqiu Zhou, Feiyi Ruan, Yuan Lu, Detection of extended-spectrum beta-lactamases in clinical isolates of Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. ,vol. 50, pp. 2990- 2995 ,(2006) , 10.1128/AAC.01511-05
T. Strateva, V. Ouzounova-Raykova, B. Markova, A. Todorova, Y. Marteva-Proevska, I. Mitov, Widespread detection of VEB-1-type extended-spectrum beta-lactamases among nosocomial ceftazidime-resistant Pseudomonas aeruginosa isolates in Sofia, Bulgaria. Journal of Chemotherapy. ,vol. 19, pp. 140- 145 ,(2007) , 10.1179/JOC.2007.19.2.140
Freshteh Shahcheraghi, Vajiheh-Sadat Nikbin, Mohammad Mehdi Feizabadi, PREVALENCE OF ESBLS GENES AMONG MULTIDRUG-RESISTANT ISOLATES OF PSEUDOMONAS AERUGINOSA ISOLATED FROM PATIENTS IN TEHRAN Microbial Drug Resistance. ,vol. 15, pp. 37- 39 ,(2009) , 10.1089/MDR.2009.0880
Carlos Juan Nicolau, Antonio Oliver, Carbapenemasas en especies del género Pseudomonas Enfermedades Infecciosas Y Microbiologia Clinica. ,vol. 28, pp. 19- 28 ,(2010) , 10.1016/S0213-005X(10)70004-5
P Nordmann, T Naas, Sequence analysis of PER-1 extended-spectrum beta-lactamase from Pseudomonas aeruginosa and comparison with class A beta-lactamases. Antimicrobial Agents and Chemotherapy. ,vol. 38, pp. 104- 114 ,(1994) , 10.1128/AAC.38.1.104
Jie Wang, Jian-ying Zhou, Ting-ting Qu, Ping Shen, Ze-qing Wei, Yun-song Yu, Lan-juan Li, Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Chinese hospitals International Journal of Antimicrobial Agents. ,vol. 35, pp. 486- 491 ,(2010) , 10.1016/J.IJANTIMICAG.2009.12.014
M.H.M. Al-Agamy, A.M. Shibl, A.F. Tawfik, H.H. Radwan, High Prevalence of Metallo-β-lactamase-Producing Pseudomonas aeruginosa from Saudi Arabia Journal of Chemotherapy. ,vol. 21, pp. 461- 462 ,(2009) , 10.1179/JOC.2009.21.4.461
Marya D. Zilberberg, Thomas Jacobsen, Glenn Tillotson, The burden of hospitalizations and emergency department visits with hereditary angioedema and angioedema in the United States, 2007. Allergy and Asthma Proceedings. ,vol. 31, pp. 511- 519 ,(2010) , 10.2500/AAP.2010.31.3403
Yvonne Pfeifer, Angela Cullik, Wolfgang Witte, Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens. International Journal of Medical Microbiology. ,vol. 300, pp. 371- 379 ,(2010) , 10.1016/J.IJMM.2010.04.005