摘要: Lung cancer is the number one cause of death; however, no specific serum biomarker available till date for detection early lung cancer. Despite good initial response to chemotherapy, small-cell (SCLC) has a poor prognosis. Therefore, it important identify molecular markers that might influence survival and may serve as potential therapeutic targets. The review aims summarize current knowledge biomarkers in SCLC improve diagnostic efficiency tumor progression on known cytokines emphasized. Recent findings search novel using emerging genomic technology detecting are also described. It believed implementing these new research techniques will facilitate detection, prognostication better treatment SCLC.