Immune thrombocytopenia following alpha-interferon therapy in patients with cancer.

摘要: Immune thrombocytopenia occurred in five patients with cancer receiving alpha-interferon. The median pretreatment platelet count was 217,000/cu mm, which fell to a of 12,000/cu mm after 25 days interferon therapy. All had normal numbers megakaryocytes, dysplasia noted three; all four who were tested platelet-associated immunoglobulin. normalization counts prednisone Four tolerated re-treatment interferon, two concurrent administration and others following splenectomy. should be considered become thrombocytopenic during