Prevalence and pattern of Helicobacter pylori gastritis in the gastric cardia.

摘要: Objectives: Helicobacter pylori has a predilection for antral colonization. Local acid production is the major determinant of Because low in antrum and cardia, H. should also colonize cardia. We therefore investigated histologic pattern gastritis prevalence cardia compared with corpus. Methods: From 135 pylori-infected patients gastritis, ulcer disease, or reflux esophagitis, biopsies were obtained from antrum, corpus, The prevalence, topography, parameters examined. Results: All had active gastritis: 132 these (97.7%) showed 124 (91.9%) visible on staining. Gastritis most resembled but density bacteria inflammatory responses less marked. striking finding gastroesophageal was lower Intestinal metaplasia found 32 mucosa (23.7%) versus 28 (20.7%), 11 corpus (8.1%), multifocal 17 (12.6%). Conclusions: commonly involves are than antrum. common gastritis. cause bacterial esophagitis needs further investigation.