Two persistent organic pollutants which act through different xenosensors (alpha-endosulfan and 2,3,7,8 tetrachlorodibenzo-p-dioxin) interact in a mixture and downregulate multiple genes involved in human hepatocyte lipid and glucose metabolism.

作者: Ariane Ambolet-Camoit , Chris Ottolenghi , Alix Leblanc , Min Ji Kim , Franck Letourneur

DOI: 10.1016/J.BIOCHI.2015.07.003

关键词:

摘要: … 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and α-endosulfan are Persistent Organic Pollutants (POPs) and endocrine disruptors which act through different xenosensors and …

参考文章(101)
P. Gripon, S. Rumin, S. Urban, J. Le Seyec, D. Glaise, I. Cannie, C. Guyomard, J. Lucas, C. Trepo, C. Guguen-Guillouzo, Infection of a human hepatoma cell line by hepatitis B virus Proceedings of the National Academy of Sciences of the United States of America. ,vol. 99, pp. 15655- 15660 ,(2002) , 10.1073/PNAS.232137699
Rong-Rong Wei, Mei-Yin Zhang, Hui-Lan Rao, Heng-Ying Pu, Hui-Zhong Zhang, Hui-Yun Wang, None, Identification of ADH4 as a novel and potential prognostic marker in hepatocellular carcinoma Medical Oncology. ,vol. 29, pp. 2737- 2743 ,(2012) , 10.1007/S12032-011-0126-3
Stephen Safe, Mark Wormke, Inhibitory aryl hydrocarbon receptor-estrogen receptor alpha cross-talk and mechanisms of action. Chemical Research in Toxicology. ,vol. 16, pp. 807- 816 ,(2003) , 10.1021/TX034036R
Michael Reich, Ted Liefeld, Joshua Gould, Jim Lerner, Pablo Tamayo, Jill P Mesirov, GenePattern 2.0. Nature Genetics. ,vol. 38, pp. 500- 501 ,(2006) , 10.1038/NG0506-500
Susumu Kodama, Rick Moore, Yukio Yamamoto, Masahiko Negishi, Human nuclear pregnane X receptor cross-talk with CREB to repress cAMP activation of the glucose-6-phosphatase gene. Biochemical Journal. ,vol. 407, pp. 373- 381 ,(2007) , 10.1042/BJ20070481
Anna-Karin M. Sjogren, Maria Liljevald, Björn Glinghammar, Johanna Sagemark, Xue-Qing Li, Anna Jonebring, Ian Cotgreave, Gabriella Brolén, Tommy B. Andersson, Critical differences in toxicity mechanisms in induced pluripotent stem cell-derived hepatocytes, hepatic cell lines and primary hepatocytes. Archives of Toxicology. ,vol. 88, pp. 1427- 1437 ,(2014) , 10.1007/S00204-014-1265-Z
Caroline Aninat, Amélie Piton, Denise Glaise, Typhen Le Charpentier, Sophie Langouët, Fabrice Morel, Christiane Guguen-Guillouzo, André Guillouzo, Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma heparg cells Drug Metabolism and Disposition. ,vol. 34, pp. 75- 83 ,(2006) , 10.1124/DMD.105.006759
Géraldine Lemaire, Wissem Mnif, Pascale Mauvais, Patrick Balaguer, Roger Rahmani, Activation of α- and β-estrogen receptors by persistent pesticides in reporter cell lines Life Sciences. ,vol. 79, pp. 1160- 1169 ,(2006) , 10.1016/J.LFS.2006.03.023
Andreas Kortenkamp, Ten Years of Mixing Cocktails: A Review of Combination Effects of Endocrine-Disrupting Chemicals Environmental Health Perspectives. ,vol. 115, pp. 98- 105 ,(2007) , 10.1289/EHP.9357