摘要: Born 1902; died 1994. Famous as a philosopher of science, Popper maintained that scientific truth is not manifest, but indeed theories are conjectures open to refutation or falsification. controversially denounced inductive reasoning—validity theory from empirical observations general regularities—insisting instead should be testing. As passes more severe tests, it becomes highly “corroborated”. He called this approach hypothetico-deductive. ‘Realism and the Aim Science’ (1982) his work most relevant biostatistics, re-examining in detail problems truth, corroboration, probability. Keywords: conjecture; refutation; induction; inference; epistemology; probability; propensity; indeterminism