Could recombinant technology facilitate the realisation of a fertility-control vaccine for possums?

作者: ML Cross , T Zheng , JA Duckworth , PE Cowan

DOI: 10.1080/03014223.2010.541468

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摘要: Abstract While lethal control remains the primary tool for possum in New Zealand, there has been substantial research effort over last decade into controlling populations by reducing animals’ breeding potential. In particular, potential of immunological to reduce fertility investigated, whereby possums’ immune system is induced react against its reproductive system, order block or destroy key components process. Two most targeted have blocking circulating hormones (e.g. gonadotrophin-releasing hormone) and inhibition functional egg surface proteins zona pellucida). some success achieved each approach, three main obstacles remain development a working fertility-control vaccine possums: first, ensuring that efficacious oral-delivery formulation; second, sufficient levels reduction; third, th...

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