Animal models for human disc degeneration.

摘要: Despite the significant impairment associated with degenerative disc disease, a clear understanding of its pathogenesis is still lacking. Currently, no particular model parallels complex nature human degeneration. Naturally occurring animal models have drawback that basis for high rate degeneration not known. Although interventions in artificial create are known, relationship those to events leading humans not. With recent progress biomechanics, cell biology and molecular biology, an easily reproducible valid may help unlock cascade surrounding