Preventive Effects of Three Polysaccharides on the Oxidative Stress Induced by Acrylamide in a Saccharomyces cerevisiae Model
作者： Zhen Lin , Yu Zhang , Fangping Li , Xiaohui Tan , Ping Luo
DOI: 10.3390/MD18080395
关键词:
摘要: Saccharomyces cerevisiae was used as a model to explore the preventive effect of two marine polysaccharides separately derived from Sepia esculenta ink (SIP) and Laminaria japonica (FL) well one terrestrial Eleocharis tuberosa peel (WCPP) on toxic injury induced by acrylamide (AA). The growth yeast evaluated kinetics indexes including doubling time, lag phase maximum proliferation density. Meanwhile, intracellular redox state determined contents MDA GSH, SOD activity. results showed that AA inhibited destroyed antioxidant defense system. Supplement with polysaccharides, oxidative damage cells alleviated. According recovery yeast, FL WCPP had similar degree capacity against associated cytotoxicity, while SIP 1.5~2 folds strong WCPP. significantly reduced production administration. Moreover, SIP, increased activity repressed GSH depletion caused AA.
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