Simulation modelling for immunologists

摘要: The immune system is inordinately complex with many interacting components determining overall outcomes. Mathematical and computational modelling provides a useful way in which the various contributions of different immunological can be probed an integrated manner. Here, we provide introductory overview review mechanistic simulation models. We start out by briefly defining these types models contrasting them to other model that are relevant field immunology. follow few specific examples then ways one use such answer questions. While our focus on responses infection, ideas descriptions uses applied any area This Review Handel colleagues focuses how used interrogate system. authors encourage immunologists build their own