Amperometric determination of paracetomol by a surface modified cobalt hexacyanoferrate graphite wax composite electrode.

摘要: A stable electro active thin film of cobalt hexacyanoferrate (CoHCF) was deposited on the surface an amine adsorbed graphite wax composite electrode using a simple method. Cyclic voltammetric experiments showed two pairs well defined peaks for this CoHCF modified which exhibited excellent electrocatalytic property oxidation paracetomol at reduced overpotential 100 mV and over concentration range 3.33x10(-6) to 1.0x10(-3)M with slope 0.208 microA/microM good sensitivity. The influence supporting electrolyte peak current potential were also obtained in addition effects common interference (e.g., ascorbic acid) response electrode. Various parameters that electrochemical behavior optimized by varying scan rates pH. Electrochemical impedance spectroscopy studies suggested reaction is mainly controlled transport counter ion. immobilized maintained its redox activity showing electron transfer rate constant (K(s)) 0.94 s(-1) charge coefficient 0.42. Hydrodynamic chronoamperometric done explore utility dynamic systems. results differential pulse voltammetry (DPV) applied determination commercially available tablets. reveal under study could be used as effective sensor online monitoring paracetomol.