Effects of a growth hormone releasing factor in man.

摘要: The effects of the 44-amino acid growth hormone releasing factor (GRF-44) were tested in normal adult men and women. At a dose 1 μg/kg intravenous boluses GRF-44 stimulated prompt elevations plasma GH, which 5 reached maximum levels 34 ± 28 (S.D.) ng/ml, 3 women mid-follicular phase, 53 10 ng/ml. action GRF was highly selective; there no changes PRL, W, FSH, TSH, or cortisol at this level. Side effects, mostly flushing sense warmth face chest, mild occurred only minority subjects.