Studies on antitumor mechanism of two planar platinum(II) complexes with 8-hydroxyquinoline: synthesis, characterization, cytotoxicity, cell cycle and apoptosis.

作者: Qi-Pin Qin , Zhen-Feng Chen , Jiao-Lan Qin , Xiao-Ju He , Yu-Lan Li

DOI: 10.1016/J.EJMECH.2014.12.052

关键词:

摘要: [Pt(Q) 2 ] (1) and [Pt(MQ) 2 ] (2) exhibited enhanced cytotoxicity against BEL-7404, Hep-G2, NCI–H460, T-24, A549 tumor cells but low cytotoxicity on normal HL-7702 cells. 1 and 2 …

参考文章(62)
E A Komarova, A V Gudkov, Suppression of p53: a New Approach to Overcome Side Effects of Antitumor Therapy Biochemistry. ,vol. 65, pp. 41- 48 ,(2000)
Aloke Raj Banerjee, John A. Jaeger, Douglas H. Turner, Thermal unfolding of a group I ribozyme: the low-temperature transition is primarily disruption of tertiary structure. Biochemistry. ,vol. 32, pp. 153- 163 ,(1993) , 10.1021/BI00052A021
Laura Bica, Jeffrey R. Liddell, Paul S. Donnelly, Clare Duncan, Aphrodite Caragounis, Irene Volitakis, Brett M. Paterson, Roberto Cappai, Alexandra Grubman, James Camakaris, Peter J. Crouch, Anthony R. White, Neuroprotective Copper Bis(thiosemicarbazonato) Complexes Promote Neurite Elongation PLoS ONE. ,vol. 9, pp. e90070- ,(2014) , 10.1371/JOURNAL.PONE.0090070
Xiantao Wang, Anthony J. Di Pasqua, Sudha Govind, Erin McCracken, Charles Hong, Lixin Mi, Yuehua Mao, Jessie Yu-Chieh Wu, York Tomita, Jordan C. Woodrick, Robert L. Fine, Fung-Lung Chung, Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships. Journal of Medicinal Chemistry. ,vol. 54, pp. 809- 816 ,(2011) , 10.1021/JM101199T
Lorne J Hofseth, S.Perwez Hussain, Curtis C Harris, p53: 25 years after its discovery. Trends in Pharmacological Sciences. ,vol. 25, pp. 177- 181 ,(2004) , 10.1016/J.TIPS.2004.02.009
Cristina Trejo-Solís, Guadalupe Palencia, Sergio Zuñiga, Andrea Rodríguez-Ropon, Laura Osorio-Rico, Sanchez Torres Luvia, Isabel Gracia-Mora, Lucrecia Marquez-Rosado, Aurora Sánchez, Miguel E. Moreno-García, Arturo Cruz, María Elena Bravo-Gómez, Lena Ruiz-Ramírez, Sara Rodríquez-Enriquez, Julio Sotelo, Cas Ilgly Induces Apoptosis in Glioma C6 Cells In Vitro and In Vivo through Caspase-Dependent and Caspase-Independent Mechanisms Neoplasia. ,vol. 7, pp. 563- 574 ,(2005) , 10.1593/NEO.04607
Kushal Sengupta, Sudipta Chatterjee, Debajyoti Pramanik, Somdatta Ghosh Dey, Abhishek Dey, Self-assembly of stable oligomeric and fibrillar aggregates of Aβ peptides relevant to Alzheimer's disease: morphology dependent Cu/heme toxicity and inhibition of PROS generation. Dalton Transactions. ,vol. 43, pp. 13377- 13383 ,(2014) , 10.1039/C4DT01991A
Luiza M.F. Gomes, Rafael P. Vieira, Michael R. Jones, Michael C.P. Wang, Christine Dyrager, Elaine M. Souza-Fagundes, Jeferson G. Da Silva, Tim Storr, Heloisa Beraldo, 8-Hydroxyquinoline Schiff-base compounds as antioxidants and modulators of copper-mediated Aβ peptide aggregation. Journal of Inorganic Biochemistry. ,vol. 139, pp. 106- 116 ,(2014) , 10.1016/J.JINORGBIO.2014.04.011
Luiza B de O Freitas, Thiago F Borgati, Rossimiriam P de Freitas, Ana LTG Ruiz, Gabriela M Marchetti, Joao E de Carvalho, Elaine FF da Cunha, Teodorico C Ramalho, Rosemeire B Alves, None, Synthesis and antiproliferative activity of 8-hydroxyquinoline derivatives containing a 1,2,3-triazole moiety. European Journal of Medicinal Chemistry. ,vol. 84, pp. 595- 604 ,(2014) , 10.1016/J.EJMECH.2014.07.061
Johnatan Ceccom, Frédéric Coslédan, Hélène Halley, Bernard Francès, Jean Michel Lassalle, Bernard Meunier, Copper chelator induced efficient episodic memory recovery in a non-transgenic Alzheimer's mouse model. PLOS ONE. ,vol. 7, ,(2012) , 10.1371/JOURNAL.PONE.0043105