Quality of Life in Head and Neck Cancer Patients

摘要: While improving the survival outcomes of head and neck cancer (HNC) patients remains primary goal advances in therapy, importance quality life (QOL) impact both tumor treatment to cannot be overemphasized. In generally, baseline QOL is among strongest available prognostic factors. Broadly speaking, a measure an individual’s overall personal well-being. instruments subjective concept, but their measurement properties are based on sound scientific principles. Evidence reliability, validity, responsiveness should required for chosen use clinical research. Poor compliance with planned questionnaires (missing data) can threaten internal external validity (generalizability); study design include strategies maximize compliance. may general (applicable population), disease-specific, symptom-specific, or treatment-specific. Disease site-specific subset cancer-specific designed specific site, such as HNC, that address concerns, xerostomia, pain, dysphagia, speech disruption. A number HNC described. Current evidence somewhat limited results ongoing trials anticipated. Future questions potential value using routine care, best translating knowledge clinicians, role computer-adaptive administration patient reported outcome measures.