Intake of phytoestrogen foods and supplements among women recently diagnosed with breast cancer in Ontario, Canada

作者: Beatrice A. Boucher , Michelle Cotterchio , Ioan A. Curca , Nancy Kreiger , Shelley A. Harris

DOI: 10.1080/01635581.2012.687426

关键词:

摘要: Phytoestrogens are found in foods such as soy (isoflavones) and flaxseed (lignans), certain botanical supplements. Their role estrogen receptor positive (ER+) breast cancer recurrence treatment is controversial, it unknown how this affects intake among patients. The Ontario Cancer Registry was used to identify 417 population-based cases (mean time from diagnosis 57 days). A questionnaire mailed determine of phytoestrogen supplements the last 2 mo, changes since differences by ER tumor status or hormonal treatment. Of 278 (67%) respondents, 56% consumed foods, 39% isoflavone-rich (tofu, soybeans, milk, nuts), 70% ate lignan-rich including (33%). Only flaxseed, bread were commonly more than once/wk. Few patients (4%) took isoflavone (soy, red clover, kudzu, licorice, isoflavones) lignan/flaxseed Since diagnosis, 17% started stopped (most stopped); prevalent those receiving (20%; 95% confidence interval (CI): 14, 26) not (6%; CI: 1, 12). No other observed. Research needed confirm explore influencing factors.

参考文章(48)
William G. Helferich, Clinton D. Allred, Young H. Ju, Suzanne M. Virant, Kimberly F. Allred, Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner. Cancer Research. ,vol. 61, pp. 5045- 5050 ,(2001)
Katayoon Pakzad, Beatrice A. Boucher, Nancy Kreiger, Michelle Cotterchio, The use of herbal and other non-vitamin, non-mineral supplements among pre- and post-menopausal women in Ontario. Canadian Journal of Public Health-revue Canadienne De Sante Publique. ,vol. 98, pp. 383- 388 ,(2007) , 10.1007/BF03405424
Per Eystein Lønning, None, Evolution of endocrine adjuvant therapy for early breast cancer. Expert Opinion on Investigational Drugs. ,vol. 19, ,(2010) , 10.1517/13543781003714865
Guri Skeie, Anette Hjartåker, Tonje Braaten, Eiliv Lund, Dietary change among breast and colorectal cancer survivors and cancer-free women in the Norwegian Women and Cancer cohort study. Cancer Causes & Control. ,vol. 20, pp. 1955- 1966 ,(2009) , 10.1007/S10552-009-9390-3
Sharon J. Wayne, Marian L. Neuhouser, Carol Koprowski, Cornelia M. Ulrich, Charles Wiggins, Frank Gilliland, Kathy B. Baumgartner, Richard N. Baumgartner, Anne McTiernan, Leslie Bernstein, Rachel Ballard-Barbash, Breast cancer survivors who use estrogenic botanical supplements have lower serum estrogen levels than non users Breast Cancer Research and Treatment. ,vol. 117, pp. 111- 119 ,(2009) , 10.1007/S10549-008-0224-X
Janice L. Daoust, Laura C. Mercer, Alison M. Duncan, Prevalence of natural health product use in healthy postmenopausal women. Menopause. ,vol. 13, pp. 241- 250 ,(2006) , 10.1097/01.GME.0000182805.91514.14
Carolyn A Lammersfeld, Jessica King, Sharon Walker, Pankaj G Vashi, James F Grutsch, Christopher G Lis, Digant Gupta, Prevalence, sources, and predictors of soy consumption in breast cancer Nutrition Journal. ,vol. 8, pp. 2- 2 ,(2009) , 10.1186/1475-2891-8-2
Jasdeep Kaur Saggar, Jianmin Chen, Paul Corey, Lilian U. Thompson, Dietary flaxseed lignan or oil combined with tamoxifen treatment affects MCF-7 tumor growth through estrogen receptor- and growth factor-signaling pathways. Molecular Nutrition & Food Research. ,vol. 54, pp. 415- 425 ,(2010) , 10.1002/MNFR.200900068