Preoperative radiotherapy improves outcome in recurrent rectal cancer

作者: Andreas Marinelli , Maarten Vermaas , Floris Ferenschild , Theo Wiggers , Wilfried Graveland

DOI: 10.1007/S00053-006-6001-6

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摘要: Purpose: When local recurrent rectal cancer is diagnosed without signs of metastases, a potentially curative resection can be performed. This study was designed to compare the results preoperative radiotherapy followed by surgery with only. Methods: Between 1985 and 2003, 117 patients were prospectively entered in our database. Ninety-two suitable for intent. Preoperative radiation median dosage 50 Gy performed 59 patients; 33 did not receive radiotherapy. The age 66 62 years, respectively. Results: follow-up alive total group 16 (range, 4-156) months. Tumor characteristics comparable between two groups. Complete resections 64% who received 45% nonirradiated patients. A complete response after found 10% preoperatively irradiated (n = 6). There no differences morbidity reintervention rate Local control statistically significantly higher three five years (p 0,036). Overall survival metastases-free different both predictive an improved survival. Conclusions: number compared treated should standard treatment cancer.

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