A clinically based prognostic index for diffuse large B-cell lymphoma with a cut-off at 70 years of age significantly improves prognostic stratification: population-based analysis from the Danish Lymphoma Registry.
作者： Anne O. Gang , Michael Pedersen , Francesco d’Amore , Lars M. Pedersen , Bo A. Jensen
DOI: 10.3109/10428194.2015.1010078
关键词:
摘要: The introduction of rituximab and generally improved health among elderly patients have increased the survival with diffuse large B-cell lymphoma (DLBCL). International Prognostic Index (IPI) from 1992 is based on pre-rituximab data clinical trials including several subtypes. We applied IPI factors to a population-based rituximab-treated cohort 1990 diagnosed 2000–2010 explored new optimal prognostic age cut-off for DLBCL. Multivariate-analyses (MVA) confirmed value all except presence > 1 extranodal lesion. was 70 years. In MVA albumin, lymphocyte count, sex, immunoglobulin G, bulky disease, hemoglobin B-symptoms, only albumin prognostic. propose: (1) modified DLBCL index (DLBCL-PI) including: (70 years), performance status (PS), lactate dehydrogenase (LDH), stage level, (2) separate age-adjusted DLBCL-PI ≤ years incl...
core.ac.uk
sci-hub.se 参考文章(34)
D. Catovsky, J. Fooks, S. Richards, Prognostic factors in chronic lymphocytic leukaemia: the importance of age, sex and response to treatment in survival British Journal of Haematology. ,vol. 72, pp. 141- 149 ,(1989) , 10.1111/J.1365-2141.1989.TB07674.X
Dai Chihara, Yasuhiro Oki, Shouji Ine, Harumi Kato, Hiroshi Onoda, Hirofumi Taji, Yoshitoyo Kagami, Kazuhito Yamamoto, Yasuo Morishima, Primary gastric diffuse large B-cell Lymphoma (DLBCL): analyses of prognostic factors and value of pretreatment FDG-PET scan European Journal of Haematology. ,vol. 84, pp. 493- 498 ,(2010) , 10.1111/J.1600-0609.2010.01426.X
Pasquale Niscola, Massimo Magagnoli, Luigi Rigacci, Umberto Vitolo, Luigi Resegotti, Carola Boccomini, Vera Clò, Luca Baldini, Pier Luigi Zinzani, Teodoro Chisesi, Maura Brugiatelli, Massimo Federico, Antonio Cuneo, Gino Santini, Marina Liberati, Giampiero Bellesi, Vincenzo Pavone, Prognosis of follicular lymphoma: a predictive model based on a retrospective analysis of 987 cases Blood. ,vol. 95, pp. 783- 789 ,(2000) , 10.1182/BLOOD.V95.3.783.003K33_783_789
Elias Campo, N Lee Harris, Elaine S Jaffe, Stefano A Pileri, Harald Stein, Jurgen Thiele, James W Vardiman, None, WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues ,(2017)
Sari Riihijärvi, Minna Taskinen, Mats Jerkeman, Sirpa Leppä, Male gender is an adverse prognostic factor in B‐cell lymphoma patients treated with immunochemotherapy* European Journal of Haematology. ,vol. 86, pp. 124- 128 ,(2011) , 10.1111/J.1600-0609.2010.01541.X
Suguru Fukuhara, Takashi Watanabe, Wataru Munakata, Masakazu Mori, Dai Maruyama, Sung-Won Kim, Yukio Kobayashi, Hirokazu Taniguchi, Akiko M. Maeshima, Ryuji Tanosaki, Yoshihiro Matsuno, Kensei Tobinai, Bulky disease has an impact on outcomes in primary diffuse large B-cell lymphoma of the breast: a retrospective analysis at a single institution. European Journal of Haematology. ,vol. 87, pp. 434- 440 ,(2011) , 10.1111/J.1600-0609.2011.01679.X
Mustaqeem Siddiqui, Kay Ristow, Svetomir N. Markovic, Thomas E. Witzig, Thomas M. Habermann, Joseph P. Colgan, David J. Inwards, William L. White, Stephen M. Ansell, Ivana N. Micallef, Patrick B. Johnston, Timothy G. Call, Luis F. Porrata, Absolute lymphocyte count predicts overall survival in follicular lymphomas British Journal of Haematology. ,vol. 134, pp. 596- 601 ,(2006) , 10.1111/J.1365-2141.2006.06232.X
Yasuhiro Oki, Kazuhito Yamamoto, Harumi Kato, Yachiyo Kuwatsuka, Hirofumi Taji, Yoshitoyo Kagami, Yasuo Morishima, Low absolute lymphocyte count is a poor prognostic marker in patients with diffuse large B-cell lymphoma and suggests patients' survival benefit from rituximab. European Journal of Haematology. ,vol. 81, pp. 448- 453 ,(2008) , 10.1111/J.1600-0609.2008.01129.X
D H Kim, J H Baek, Y S Chae, Y-K Kim, H J Kim, Y H Park, H S Song, J S Chung, M S Hyun, S K Sohn, Absolute lymphocyte counts predicts response to chemotherapy and survival in diffuse large B-cell lymphoma Leukemia. ,vol. 21, pp. 2227- 2230 ,(2007) , 10.1038/SJ.LEU.2404780
Dipti Talaulikar, Ayesha Choudhury, Bruce Shadbolt, Michael Brown, Lymphocytopenia as a prognostic marker for diffuse large B cell lymphomas. Leukemia & Lymphoma. ,vol. 49, pp. 959- 964 ,(2008) , 10.1080/10428190801959026