METHOD OF DIAGNOSTICS OF ENDOTHELIAL, NEUROGENIC AND MYOGENIC MECHANISMS OF MICROVESSELS TONUS REGULATION AND ELECTRONIC THERMAL RECORDER FOR ITS IMPLEMENTATION

作者: Podtaev Sergej Yurevich

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摘要: FIELD: medicine.SUBSTANCE: group of inventions refers to medicine, namely functional diagnostics, and can be used study the violations mechanisms microvessels tonus regulation. Method investigation includes recording changes in vascular during after a load. In this case, data processing is performed using continuous wavelet analysis frequency bands corresponding endothelial (0.0095–0.02 Hz), neurogenic (> 0.02–0.05 myogenic (> 0.05–0.14 Hz) As load, heat test performed. To do this, temperature patient's area patient recorded continuously. During first 1–2 minutes, skin surface under increased 38–42 oC. Fix heating power order maintain constant average being examined. Record fluctuations 10 minutes sample turn off heating. Then, for switching cooling 30–32 oC, registration continued. based on comparative variations values thermal sample, mechanism disturbances regulation judged. Electronic recorder carrying out method according invention comprises remote sensor provided with unit, an analog-to-digital converter, microcontroller that transmits personal computer through interface. One chip ADC contains three-channel multiplexer, instrument amplifier, reference voltage source, controlled current source sigma-delta unit itself. Microcontroller Flash program memory, RAM, non-volatile UART interface PC communication, SPI communication ADC. Temperature logger optoisolator between measuring circuit, circuit PC, supply galvanic isolation unit. Remote bridge thermistor SMD resistor block.EFFECT: increase accuracy, reliability, simplification studies achieved.7 cl, 1 dwg, 3 ex, 2 tbl

参考文章(8)
Arye Rosen, William P. Santamore, Method of measuring blood perfusion ,(1978)
Morteza Naghavi, Timothy O'Brien, Craig Jamieson, Mark Johnson, Method and apparatus for determining vascular health conditions ,(2007)
Podtaev Sergej Jur Evich, Morozov Matvej Konstantinovich, Ershova Anna Il Inichna, Zhukova Evgenija Aleksandrovna, Popov Aleksandr Vladimirovich, METHOD FOR DIAGNOSTICS OF ENDOTHELIAL DYSFUNCTION IN DIABETES MELLITUS PATIENTS ,(2010)
Podtaev Sergej Jur Evich, Morozov Matvej Konstantinovich, Ershova Anna Il Inichna, Popov Aleksandr Vladimirovich, METHOD FOR RECORDING BLOOD MICROCIRCULATION ,(2010)
Gvazdajtis Antanas I, Klumbis Egidiyus L, Mikulenas Gediminas B, Klumbis Leonas A, METHOD FOR EVALUATING FUNCTIONAL STATE CEREBRAL VESSELS ,(1991)
Zhang Jiayong, Zhang Guiping, Liu Xing, Liang Zhaoyun, Huang Dequn, Chen Jun, Zhu Bin, Vascular endothelial function detecting device based on fingertip temperature change ,(2014)