Localisation of thiamine pyrophosphatase in the amoeboid microglial cells in the brain of postnatal rats.

摘要: The activity of TPPase in amoeboid microglial cells has been studied postnatal rats. When examined with the light microscope such 1-10 days old rats perfused 4% paraformaldehyde were round and showed a dark brown reaction their cytoplasm. In older (10-30 days), reactive oval, flattened or branched. Electron microscopic examination revealed that product was seen on plasma membrane, subplasmalemmal vacuoles, tubular invaginations membrane transface Golgi saccules. mixed aldehyde solution, did not show positive but at ultrastructural level weak some cytoplasmic vacuoles