Global properties of a cell mediated immunity in HIV infection model with two classes of target cells and distributed delays
作者： A. M. Elaiw , R. M. Abukwaik , E. O. Alzahrani
DOI: 10.1142/S1793524514500557
关键词:
摘要: In this paper, we study the global properties of a human immunodeficiency virus (HIV) infection model with cytotoxic T lymphocytes (CTL) immune response. The is six-dimensional that describes interaction HIV two classes target cells, CD4+ cells and macrophages. rate given by saturation functional Two types distributed time delays are incorporated into to describe needed for cell replication. Using method Lyapunov functional, have established stability determined threshold numbers, basic reproduction number R0 response activation . We proven if ≤ 1, then uninfected steady state globally asymptotically stable (GAS), , infected without CTL GAS, GAS.
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