Pooled analysis of the surgical treatment for colorectal cancer liver metastases

摘要: Liver metastases in colorectal cancer patients decreases the expected 5 year survival rates by a factor close to nine. It is generally accepted that resection of liver should be attempted whenever feasible. This manuscript addresses optimal therapeutic plan regarding timing synchronous and use chemotherapy combination with metachronous metastases. The aim pool all published results order attribute level evidence outcomes identify lacking areas. A systematic search guidelines, reviews, randomised controlled, observational studies updating meta-analysis was performed. Data were extracted analysed. failed demonstrate an effect surgery or on overall survival. Concomitant primary tumour may result lower postoperative morbidity. Systemic peri-operative improve progression free compared alone.