Huntington disease-unaffected fetus diagnosed from maternal plasma using QF-PCR.

摘要: The discovery of fetal DNA in maternal plasma from early pregnancies has led to new opportunities for clinical application. In the last few years there have been numerous reported applications, mainly gender and RhD genotyping. prenatal diagnosis some inherited genetic diseases such as Huntington disease is also very frequently required routine. We successfully diagnosed, with a non-invasive procedure, an unaffected HD fetus at 13th week gestation using quantitative fluorescent PCR method, which one most sensitive ways detect time gestation.