EFFECT OF PROPRANOLOL AND PRAZOSIN ON BLOOD LIPIDS: The Oslo Study
作者： P. Leren , A. Helgeland , I. Holme , P.O. Foss , I. Hjermann
DOI: 10.1016/S0140-6736(80)92888-3
关键词:
摘要: Abstract In 23 hypertensive men, aged 47-55, propranolol reduced serum high-density-lipoprotein (HDL) cholesterol by 13%, the ratio of HDL to low-density-lipoprotein (LDL)+very-low-density-lipoprotein (VLDL) 15%, increased total triglycerides 24%, and uric acid 10%. Prazosin 9%, LDL+VLDL 10%, 16%. These changes are statistically highly significant. On combined treatment with prazosin was still significantly but in other blood lipids were small insignificant. Uric remained elevated. When decisions about long-term therapy made, such metabolic effects might be special importance.
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