Therapeutic formulations for the treatment of beta-amyloid related diseases

作者: Francesco Bellini , Francine Gervais

DOI:

关键词:

摘要: This invention relates to methods and pharmaceutical compositions for treating amyloid-s related diseases, including Alzheimer's disease. The invention, example, includes a method of concomitant therapeutic treatment subject, comprising administering an effective amount first agent second agent, wherein said treats disease, neurodegeneration, or cellular toxicity; is drug nutritive supplement.

参考文章(18)
Paola Rocca, Elena Cocuzza, Livio Marchiaro, Filippo Bogetto, Donepezil in the treatment of Alzheimer's disease: Long-term efficacy and safety Progress in Neuro-psychopharmacology & Biological Psychiatry. ,vol. 26, pp. 369- 373 ,(2002) , 10.1016/S0278-5846(01)00283-4
Nathaniel Gavin Nicolas Milton, Peptides for use in the treatment of alzheimer's disease ,(2001)
Francine Gervais, Celine Morissette, Method for modulating macrophage activation ,(1999)
Francine Gervais, Robert Chalifour, Ajay Gupta, Stereoselective antifibrillogenic peptides and peptidomimetics thereof ,(2000)
Mark A. Findeis, Ethan R. Signer, James Wakefield, Gary Musso, Malcolm L. Gefter, Michael Kelley, Sonja Komar-Panicucci, Jung-Ja Lee, Joseph Chin, Kathryn Phillips, Neil J. Hayward, Susan Molineaux, Christopher C. Arico-Muendel, Modulators of beta-amyloid peptide aggregation comprising d-amino acids ,(2000)
Robert Kisilevsky, Laura J. Lemieux, Paul E. Fraser, Xianqi Kong, Philip G. Hultin, Walter A. Szarek, Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: implications for Alzheimer's disease Nature Medicine. ,vol. 1, pp. 143- 148 ,(1995) , 10.1038/NM0295-143
Edith G McGeer, Patrick L McGeer, Clinically tested drugs for Alzheimer's disease. Expert Opinion on Investigational Drugs. ,vol. 12, pp. 1143- 1151 ,(2003) , 10.1517/13543784.12.7.1143
Santiago Conde, β-Amyloid peptide as a target for treatment of Alzheimer’s disease Expert Opinion on Therapeutic Patents. ,vol. 12, pp. 503- 512 ,(2002) , 10.1517/13543776.12.4.503