The histochemical localization of cytochrome oxidase in the retina and lateral geniculate nucleus of the ferret, cat, and monkey, with particular reference to retinal mosaics and ON/OFF-center visual channels

摘要: The histochemical localization of cytochrome oxidase within the normal retina and lateral geniculate nucleus (LGN) cats, ferrets, monkeys revealed that distinct layers, types cells, portions neurons are more intensely stained than others. dark staining photoreceptor inner segments cone pedicles light outer segments, somata, rod spherules demonstrates different same cell may have disparate but levels oxidative enzyme activity. In tangential sections retina, regular mosaic arrays were evident for each several darkly reactive retinal components, such as pedicles, horizontal cells. cat ferret, also formed by metabolically distinguishable populations ganglion Ia IIa cells (OFF-; Nelson, R., E. V. Famiglietti, Jr., H. Kolb (1978) J. Neurophysiol. 41: 472–483) other classes. darker sublamina a plexiform layer V., (1976) Science 194: 193–195) in ferret well A′ A1′ LGN Stryker, M.P., K.R. Zahs (1983a) Neurosci. 3: 1943–1951) suggest that, under typical rearing conditions, OFF-channels be active ON-channels these species. Macaca Saimiri, was observed b (ON-; E.V., laminae 1, 2, 6 LGN, implying similar pattern is observed. many large most larger (presumed Y/Y-like), all species studied evidence Y/Y-like pathway highly active.