Nutraceuticals and cardiovascular risk: potential role of EPCs modulation

摘要: According to WHO cardiovascular diseases (CVDs) are the first cause of death in world: more people die annually from CVDs than any other cause. Vascular endothelium plays a pivotal role onset and progression these pathologies risk factors frequently associated levels endothelial progenitor cells (EPCs), bone marrow-derived circulating progenitors for lineage. Since EPCs not only preserve vascular homeostasis, but directly participate re-endothelization neovascularization, represent an emerging actor competence thus cell model great interest. An unhealthy diet is one main factor; there indeed interest potential  protective effects "nutraceuticals,", food-derived compounds that exert beneficial on human animal health. The characterization different nutraceuticals may provide fresh insights into their prevention. Several studies have already showed protective natural antioxidants functionality; some examples resveratrol, catechin folic acid. Fermentation has recently shown interesting roles prevention since this process created new class food, rich bioactive compounds, fermented food. Consumption legumes cereals, also beverages (such as beer wine) was found protect function through lipid-lowering, anti-inflammatory antioxidative mechanisms. Little known about fermentation-derived given important biomarker, further analysis field can improve treatment.