Dyslipidemia Induced by Stress

摘要: The pioneering work of Hans Selye (1936) led to the use word “stress” in a biological context gaining popularity world-wide. Stress is as an organic response stressors that can be aversive stimuli or unknown situations capable compromising homeostasis. During stress reaction, sympathetic nervous system and hypothalamic–pituitary–adrenal axis are stimulated. Consequently, serum concentrations classical hormones, namely catecholamines glucocorticoids, increased act on cells tissues inducing adaptive changes order protect organism allow its survival. In addition, reaction also modulate immune activities secretion other hormones (gonadotrophins, estrogen, testosterone, thyroid, angiotensins). Considering homeostatic systems subject frequent environmental internal variations, Sterling Eyer (1988) proposed term alostasis describe adaptative processes actively maintain stability through physiological changes. terms eustress efficient allostasis facile adaptation, such quick peak mobilize energy deal with acute stressor, rapid return baseline, when stressor terminates. On hand, distress allostatic load refers imbalance promote adaptation (Epel, 2009; Korte et al., 2005). This simply result too much repeated stress, but it out balance fail shut-off or, alternatively, normal 2009). Therefore particularly important, because, do not shut off time, they cause damage pathology (McEwen, 1998). glucocorticoids (cortisol) (epinephrine norepinephrine), catabolic breakdown glycogen, triglycerides proteins into molecules rapidly metabolized generate (Black, 2002). These responses enable substrates directed organs