High risk of occult hepatitis B virus infection in leukemia patients from China

作者: Zhenhua Zhang , Yafei Zhang , Nan Xu , Cheng Huang , Xu Li

DOI: 10.1007/S00705-016-3111-5

关键词:

摘要: In this study, we assessed the prevalence of overt and occult hepatitis B virus (HBV) infection among leukemia patients. Among 256 patients 377 fracture (control group), found that surface-antigen-positive rate was greater in than controls (odds ratio, 2.08; p = 0.01). Moreover, HBV higher (10.5 % vs. 2.9 %; odds 3.92; < 0.001). The genotype distribution differed significantly between chronic or control groups (p 0.001 0.01, respectively); specifically, C primarily observed with leukemia. stop codon mutation amino acid substitutions major hydrophilic region did not differ groups. Thus, is patients, differs infection.

参考文章(33)
Meng-ji Lu, Ling Zhang, Zhen-hua Zhang, Dong-liang Yang, Xu Li, Establishment of reference sequences of hepatitis B virus genotype B and C in China Chinese Journal of Hepatology. ,vol. 17, pp. 891- 895 ,(2009) , 10.3760/CMA.J.ISSN.1007-3418.2009.12.003
Jiu-Hong Li, Hao Guo, Xing-Hua Gao, Hong-Duo Chen, Multiple skin ulcers from malignant syphilis The Lancet. ,vol. 386, pp. 1564- ,(2015) , 10.1016/S0140-6736(15)60157-X
Z‐H Zhang, L Li, X‐P Zhao, D Glebe, CM Bremer, Z‐M Zhang, Y‐J Tian, B‐J Wang, Y Yang, W Gerlich, M Roggendorf, X Li, M Lu, D‐L Yang, None, Elimination of hepatitis B virus surface antigen and appearance of neutralizing antibodies in chronically infected patients without viral clearance Journal of Viral Hepatitis. ,vol. 18, pp. 424- 433 ,(2011) , 10.1111/J.1365-2893.2010.01322.X
Ji Won Han, Hyun Yang, Hae Lim Lee, Si Hyun Bae, Jong Young Choi, Jong-Wook Lee, Hee Je Kim, Seok Lee, Seok Goo Cho, Chang Ki Min, Dong Wook Kim, Seung Kew Yoon, Risk factors and outcomes of hepatitis B virus reactivation in hepatitis B surface antigen negative patients with hematological malignancies Hepatology Research. ,vol. 46, pp. 657- 668 ,(2016) , 10.1111/HEPR.12603
Karin Kidd-Ljunggren, Ole Simonsen, Reappearance of hepatitis B 10 years after kidney transplantation. The New England Journal of Medicine. ,vol. 341, pp. 127- 128 ,(1999) , 10.1056/NEJM199907083410213
He Huang, Xueying Li, Jun Zhu, Sheng Ye, Hongyu Zhang, Wei Wang, Xiangyuan Wu, Jiewen Peng, Bing Xu, Yingcheng Lin, Yabing Cao, Haoran Li, Suxia Lin, Qing Liu, Tongyu Lin, Entecavir vs lamivudine for prevention of hepatitis B virus reactivation among patients with untreated diffuse large B-cell lymphoma receiving R-CHOP chemotherapy: a randomized clinical trial. JAMA. ,vol. 312, pp. 2521- 2530 ,(2014) , 10.1001/JAMA.2014.15704
Zhuanbo Luo, Lanjuan Li, Bing Ruan, None, Impact of the implementation of a vaccination strategy on hepatitis B virus infections in China over a 20-year period International Journal of Infectious Diseases. ,vol. 16, pp. 82- 88 ,(2012) , 10.1016/J.IJID.2011.10.009
Ke-Qin Hu, Occult hepatitis B virus infection and its clinical implications. Journal of Viral Hepatitis. ,vol. 9, pp. 243- 257 ,(2002) , 10.1046/J.1365-2893.2002.00344.X
Timm H. Westhoff, Friederike Jochimsen, Alexander Schmittel, Marina Stöffler-Meilicke, Jürgen H. Schäfer, Walter Zidek, Wolfram H. Gerlich, Eckhard Thiel, Fatal hepatitis B virus reactivation by an escape mutant following rituximab therapy Blood. ,vol. 102, pp. 1930- 1930 ,(2003) , 10.1182/BLOOD-2003-05-1403
Marcus Altfeld, Jurgen K. Rockstroh, Marylyn Addo, Bernd Kupfer, Irmgard Pult, Hans Will, Ulrich Spengler, Reactivation of hepatitis B in a long-term anti-HBs-positive patient with AIDS following lamivudine withdrawal Journal of Hepatology. ,vol. 29, pp. 306- 309 ,(1998) , 10.1016/S0168-8278(98)80017-2