Diet supplementation with green tea extract epigallocatechin gallate prevents progression to glucose intolerance in db/db mice.

摘要: Background Green tea was suggested as a therapeutic agent for the treatment of diabetes more than 70 years ago, but mechanisms behind its antidiabetic effect remains elusive. In this work, we address issue by feeding green extract (TEAVIGO™) with high content epigallocatechin gallate (EGCG) or thiazolidinedione PPAR-γ agonist rosiglitazone, positive control, to db/db mice, an animal model diabetes.