SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood from the San Francisco Bay Area
作者： Dianna L. Ng , Gregory M. Goldgof , Brian R. Shy , Andrew G. Levine , Joanna Balcerek
DOI: 10.1101/2020.05.19.20107482
关键词:
摘要: We report very low SARS-CoV-2 seroprevalence in two San Francisco Bay Area populations. Seropositivity was 0.26% 387 hospitalized patients admitted for non-respiratory indications and 0.1% 1,000 blood donors. additionally describe the longitudinal dynamics of immunoglobulin-G, immunoglobulin-M, vitro neutralizing antibody titers COVID-19 patients. Neutralizing antibodies rise tandem with immunoglobulin levels following symptom onset, exhibiting median time to seroconversion within one day each other, there is >93% positive percent agreement between detection immunoglobulin-G titers.
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