The Use of Human Biological Measurements for Safety Evaluation in the Chemical Industry

摘要: Although man has been exposed to naturally occurring poisons since the beginning of his existence, it is only in past 80 years that there a dramatic increase number synthetic chemicals, few which have subsequently shown cause health problems following human exposure. However, this country better than times and expectation life chemical age longer ever before[l]. There no evidence mass harm population from new substances[2,3]. In industry, history effects usually resulted specific exposures; for example: bladder cancer exposure aromatic amines, fibrotic lung disease silica dust, mesothelioma asbestos, occupational asthma platinum salts more recently angiosarcoma liver vinyl chloride monomer. As well as industrial situation, chemicals pharmaceutical preparations, domestic products, food additives, pesticide residues accidental contamination environment.