Metal Ion-Induced Self-Assembly and Packaging of CCMV Nanocapsules.
作者： Lise Schoonen , Mark B. van Eldijk , Jan C. M. van Hest
DOI: 10.1007/978-1-4939-7893-9_5
关键词:
摘要: The controlled self-assembly of protein cages is vital for the use these nanocompartments in biomedical and nanotechnological applications. Recently, we showed that by combining different structural peptide elements, it possible to assemble viral capsid proteins distinct well-defined morphologies. In this chapter, a triblock copolypeptide discussed, consisting metal ion-coordinating hexahistidine tag, stimulus-responsive elastin-like polypeptide pH-responsive self-assembling protein. This able form two types capsids, depending on assembly pathway followed. Here, focus ion-induced process describe relevant experimental procedures induce utilize behavior.
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