Retinal astrocytic hamartomas in tuberous sclerosis complex

摘要: A3-month-old baby (born 36/40weeks)with antenatal diagnosis of tuberous sclerosis (TS) (having cardiac rhadomyomas and multiple subependymal nodules) was admitted with new onset infantile spasms. Electroencephalography revealed modified hypsarrhythmia. The spasms were managedwith Vigabatrin. Magnetic resonance imaging the brain reveadled subcortical tubers scattered throughout both cerebral hemispheres in keeping TS (Figs 1a 1b). Two very tiny retinal masses, hypointense on T2-weighted images moderately enhancing post gadolinium T1-weighted noted within left eye, suggestive astrocytic hamartomas 2 3). Thesefindingswere further confirmed orbital ultrasound that welldefined masses eye (Fig. 4). Ophthalmic examination under anesthesia eye. Her recent ophthalmic examination, at age years demonstrated stable appearance lesions. Retinal are known ocular manifestation complex [1]. largest reported