A new family of fluorescent pyridazinobenzimidazolium cations with DNA binding properties
作者： Francisco Mendicuti , David Sucunza , Gema Marcelo , Juan J. Vaquero , Alberto Domingo
DOI: 10.1016/J.DYEPIG.2021.109443
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摘要: Abstract A series of novel azonia aromatic heterocycles formed by a pyridazinobenzimidazolium system has been synthesized. Spectrofluorimetric and circular dichroism measurements, as well theoretical simulations for these materials, have shown their interesting fluorescence properties DNA-binding ability. Stoichiometries binding constants were obtained the induced spectra analysis. Moreover, potential compounds cell staining investigated in living HeLa cells confocal microscopy imaging.
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