Fluorometric Biosniffer Camera "Sniff-Cam" for Direct Imaging of Gaseous Ethanol in Breath and Transdermal Vapor.
作者： Takahiro Arakawa , Toshiyuki Sato , Kenta Iitani , Koji Toma , Kohji Mitsubayashi
DOI: 10.1021/ACS.ANALCHEM.6B04676
关键词:
摘要: Various volatile organic compounds can be found in human transpiration, breath and body odor. In this paper, a novel two-dimensional fluorometric imaging system, known as "sniffer-cam" for ethanol vapor released from palm skin was constructed validated. This system measures concentrations intensities of fluorescence through an enzymatic reaction induced by alcohol dehydrogenase (ADH). The consisted multiple ultraviolet light emitting diode (UV-LED) excitation sheet, ADH enzyme immobilized mesh substrate high-sensitive CCD camera. uses recognition vapor. It measuring nicotinamide adenine dinucleotide (NADH), which is produced on the mesh. NADH achieved real-time distribution (0.5-200 ppm). showed rapid accurate responses visible measurement, could lead to analysis metabolism function at real time near future.
acs.org
sci-hub.se 参考文章(24)
Hiroyuki Kudo, Masayuki Sawai, Yuki Suzuki, Xin Wang, Tomoko Gessei, Daishi Takahashi, Takahiro Arakawa, Kohji Mitsubayashi, Fiber-optic bio-sniffer (biochemical gas sensor) for high-selective monitoring of ethanol vapor using 335 nm UV-LED Sensors and Actuators B-chemical. ,vol. 147, pp. 676- 680 ,(2010) , 10.1016/J.SNB.2010.03.066
Laurent Dormont, Jean-Marie Bessière, Anna Cohuet, Human skin volatiles: a review Journal of Chemical Ecology. ,vol. 39, pp. 569- 578 ,(2013) , 10.1007/S10886-013-0286-Z
Shin-Ichi Ohira, Kei Toda, Micro gas analyzers for environmental and medical applications. Analytica Chimica Acta. ,vol. 619, pp. 143- 156 ,(2008) , 10.1016/J.ACA.2008.05.010
M.A. Dumett, I.G. Rosen, J. Sabat, A. Shaman, L. Tempelman, C. Wang, R.M. Swift, Deconvolving an Estimate of Breath Measured Blood Alcohol Concentration from Biosensor Collected Transdermal Ethanol Data. Applied Mathematics and Computation. ,vol. 196, pp. 724- 743 ,(2008) , 10.1016/J.AMC.2007.07.026
Tomoya Kamei, Takao Tsuda, Yuuko Mibu, Shinya Kitagawa, Hiroko Wada, Ken Naitoh, Koji Nakashima, Novel instrumentation for determination of ethanol concentrations in human perspiration by gas chromatography and a good interrelationship between ethanol concentrations in sweat and blood Analytica Chimica Acta. ,vol. 365, pp. 259- 266 ,(1998) , 10.1016/S0003-2670(97)00673-9
Takahiro Arakawa, Xin Wang, Takumi Kajiro, Kumiko Miyajima, Shuhei Takeuchi, Hiroyuki Kudo, Kazuyoshi Yano, Kohji Mitsubayashi, None, A direct gaseous ethanol imaging system for analysis of alcohol metabolism from exhaled breath Sensors and Actuators B-chemical. ,vol. 186, pp. 27- 33 ,(2013) , 10.1016/J.SNB.2013.05.071
L. Pauling, A. B. Robinson, R. Teranishi, P. Cary, Quantitative Analysis of Urine Vapor and Breath by Gas-Liquid Partition Chromatography Proceedings of the National Academy of Sciences of the United States of America. ,vol. 68, pp. 2374- 2376 ,(1971) , 10.1073/PNAS.68.10.2374
Anton Amann, Pawel Mochalski, Vera Ruzsanyi, Yoav Y Broza, Hossam Haick, Assessment of the exhalation kinetics of volatile cancer biomarkers based on their physicochemical properties. Journal of Breath Research. ,vol. 8, pp. 016003- 016003 ,(2014) , 10.1088/1752-7155/8/1/016003
Ming Ye, Po-Jen Chien, Koji Toma, Takahiro Arakawa, Kohji Mitsubayashi, An acetone bio-sniffer (gas phase biosensor) enabling assessment of lipid metabolism from exhaled breath Biosensors and Bioelectronics. ,vol. 73, pp. 208- 213 ,(2015) , 10.1016/J.BIOS.2015.04.023
Yekbun Adiguzel, Haluk Kulah, Breath sensors for lung cancer diagnosis Biosensors and Bioelectronics. ,vol. 65, pp. 121- 138 ,(2015) , 10.1016/J.BIOS.2014.10.023