Salivary IgA as a Potential Biomarker in the Evaluation of Respiratory Tract Infection Risk in Athletes

摘要: In recent years, there has been attention focused on the value of salivary IgA (sIgA) as a potential biomarker for identification athletes who may be at increased risk developing respiratory tract infection (RTI). The utility sIgA, in this context, is based biological plausibility and several observational studies revealing an apparent association between sIgA RTI susceptibility. overall published evidence evaluating context however conflicting, currently lack clear guidance to whether marker place health surveillance care athletes. review, we critically appraise literature assessing used it against 4 key characteristics, including its (1) practicality, (2) reproducibility, (3) specificity/sensitivity, (4) clinical impact relevance. This process reveals that although illness many studies, with some promising results, remains paucity supporting context. Key deficiencies metrics employed endorse valid are apparent, reproducibility low specificity sensitivity detection review outlines these issues makes future recommendations.