Intraductal dysplasia: A premalignant lesion of the prostate

摘要: Foci of cytologic atypia with some the histologic features malignancy were identified in ductal and acinar lining epithelia from 100 serially blocked prostates adenocarcinoma benign obtained at autopsy. Criteria for diagnosis grading severity established this lesion, which is referred to as intraductal dysplasia. The features, extent, dysplasia compared between two groups. Eighty-two carcinoma 43 contained foci (grade) extent greater carcinoma. Grade 3 was found 33 per cent cancer but only 4 prostates. frequency multiple, independent invasive carcinomas high among multiple dyplasia. It concluded that probably a direct biologic precursor prostatic may be antecedent lesion majority cancers.