Methods and systems for experimental set-up and data analysis in targeted proteomics applications

作者: Reto Ossola , Claudia Escher , Lukas Reiter , Oliver Rinner

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摘要: A method of the analysis compounds with mass spectrometry and to instruments, substances, methods for polypeptide analysis, in particular targeted proteomics applications based on indexed retention times as peptide specific property. The chemical comprises steps of: a) providing a first sample comprising peptides; b) performing LC-MS determining empirical time values c) translating into scale associating reference value; d) second complex e) values; f) peptides by numerically adapting transformation function; g) predicted value using adapted function determined step f).

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