Biofilm formation on nanostructured hydroxyapatite-coated titanium.

作者: Emma Westas , Martin Gillstedt , Jessica Lönn-Stensrud , Ellen Bruzell , Martin Andersson

DOI: 10.1002/JBM.A.34757

关键词:

摘要: Biofilm formation on medical devices is a common cause of implant failure, especially regarding implants that breach the epithelial tissue, so-called transcutaneous implants. Nanotechnology and development new nanomaterials have given opportunity to design nanotextured surfaces. Such surfaces been studied using various in vitro methods showing nanosized features strongly benefit bone cell growth. However, little known how nanostructured affect biofilm formation. The aim this study was therefore examine shape- chemical-dependent effect hydroxyapatite (HA) coating degree Staphylococcus epidermidis Three different types HA particles having shapes calcium phosphate ratios were compared uncoated turned titanium safranin stain assay confocal laser scanning microscopy (CLSM) for assessment biomass bacterial volume, respectively. No difference detected after 6 h incubation with S. epidermidis. Additionally, image analysis CLSM Z-stacks confirmed showed similar results. In conclusion, nanomorphology chemical composition surface coatings did not influence adhesion

参考文章(30)
L. Montanaro, D. Campoccia, C.R. Arciola, Nanostructured materials for inhibition of bacterial adhesion in orthopedic implants: a minireview. International Journal of Artificial Organs. ,vol. 31, pp. 771- 776 ,(2008) , 10.1177/039139880803100904
D. Campoccia, L. Montanaro, H. Agheli, D.S. Sutherland, V. Pirini, M.E. Donati, C.R. Arciola, Study of Staphylococcus aureus adhesion on a novel nanostructured surface by chemiluminometry International Journal of Artificial Organs. ,vol. 29, pp. 622- 629 ,(2006) , 10.1177/039139880602900612
Ryo Jimbo, Javier Sotres, Carina Johansson, Karin Breding, Fredrik Currie, Ann Wennerberg, The biological response to three different nanostructures applied on smooth implant surfaces Clinical Oral Implants Research. ,vol. 23, pp. 706- 712 ,(2012) , 10.1111/J.1600-0501.2011.02182.X
V. Fröjd, L. Chávez de Paz, M. Andersson, A. Wennerberg, J.R. Davies, G. Svensäter, In situ analysis of multispecies biofilm formation on customized titanium surfaces. Molecular Oral Microbiology. ,vol. 26, pp. 241- 252 ,(2011) , 10.1111/J.2041-1014.2011.00610.X
Luiz Meirelles, Anna Arvidsson, Martin Andersson, Per Kjellin, Tomas Albrektsson, Ann Wennerberg, Nano hydroxyapatite structures influence early bone formation Journal of Biomedical Materials Research Part A. ,vol. 87, pp. 299- 307 ,(2008) , 10.1002/JBM.A.31744
Sabrina D. Puckett, Phin Peng Lee, Deborah M. Ciombor, Roy K. Aaron, Thomas J. Webster, Nanotextured titanium surfaces for enhancing skin growth on transcutaneous osseointegrated devices. Acta Biomaterialia. ,vol. 6, pp. 2352- 2362 ,(2010) , 10.1016/J.ACTBIO.2009.12.016
Carmen Giordano, Enrica Saino, Lia Rimondini, Maria Pia Pedeferri, Livia Visai, Alberto Cigada, Roberto Chiesa, Electrochemically induced anatase inhibits bacterial colonization on Titanium Grade 2 and Ti6Al4V alloy for dental and orthopedic devices Colloids and Surfaces B: Biointerfaces. ,vol. 88, pp. 648- 655 ,(2011) , 10.1016/J.COLSURFB.2011.07.054
Changli Zhao, Weiping Ji, Pei Han, Jihong Zhang, Yao Jiang, Xiaonong Zhang, In vitro and in vivo mineralization and osseointegration of nanostructured Ti6Al4V Journal of Nanoparticle Research. ,vol. 13, pp. 645- 654 ,(2011) , 10.1007/S11051-010-0061-9
Thomas J Thomas Webster, Greater osteoblast and endothelial cell adhesion on nanostructured polyethylene and titanium International Journal of Nanomedicine. ,vol. 5, pp. 647- 652 ,(2010) , 10.2147/IJN.S13047