Antimicrobial Activity of Essential Oils against Helicobacter pylori
作者： Tomoyuki Ohno , Masakazu Kita , Yoshio Yamaoka , Shigeyoshi Imamura , Toshiro Yamamoto
DOI: 10.1046/J.1523-5378.2003.00146.X
关键词:
摘要: Background.Helicobacter pylori is an important pathogen responsible for gastroduodenal diseases in humans. Although the eradication of H. pylori using antibiotics often improves diseases, resistance to emerging. Materials and Methods. The antimicrobial effect essential oils development were evaluated vitro vivo. Results. Thirteen used this study completely inhibited growth at a concentration 0.1% (v/v). Cymbopogon citratus (lemongrass) Lippia citriodora (lemon verbena) bactericidal against 0.01% pH 4.0 5.0. Resistance lemongrass did not develop even after 10 sequential passages, whereas clarithromycin developed under same conditions. In vivo studies, density stomach mice treated with was significantly reduced compared untreated mice. Conclusions. These results demonstrate that are without acquired resistance, suggesting may have potential as new safe agents inclusion anti-H. regimens.
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