Periodic events and cell cycle regulation in the plasmodia ofPhysarum polycephalum
作者： R. Vimala Nair
DOI: 10.1007/BF02711585
关键词:
摘要: The multinucleated plasmodia ofPhysarum polycephalum, a myxomycete, have been extensively used in cell cycle studies. natural synchrony of mitosis and DNA synthesis, easy culture methods, the ready fusions obtainable between plasmodia, amenability to phase specific studies, employing physical chemical perturbers, are some attractive features this organism. Because absence Gl there is crowding marker events at G2/M boundary, which reflect both Gl/S boundaries typical eukaryotic cell. Prominent among these synthesis overall activity thymidine kinase, co-triggering tubulin histone genes, translation their mRNA, organization duplication microtubular organizing centres mitotic spindle triggering cdc 2 kinase activity. These above not only served as good markers monitor progress plasmodial cycle, but also fairly thoroughly analysed by means perturbers such inhibitors, antimicrotubular drugs, UV-irradiation, heat-shock etc. Along with fusion perturbation studies helpful formulation various models on regulation mitosis. aspects well prospects for future organism discussed
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Timothy G. Burland, Genetic Analysis in Physarum polycephalum Springer, Boston, MA. pp. 19- 38 ,(1986) , 10.1007/978-1-4613-2203-0_2
M Wright, B Ducommun, Variation of tubulin half-life during the cell cycle in the synchronous plasmodia of Physarum polycephalum. European Journal of Cell Biology. ,vol. 50, pp. 48- 55 ,(1989)
K.-E. Wohlfarth-Bottermann, Biological Aspects of Motility Springer, Boston, MA. pp. 151- 163 ,(1986) , 10.1007/978-1-4613-2203-0_8
Ulrich Ryser, Die Ultrastruktur der Mitosekerne in den Plasmodien von Physarum polycephalum Cell and Tissue Research. ,vol. 110, pp. 108- 130 ,(1970) , 10.1007/BF00343989
Timothy G. Burland, Lilianna Solnicakrezel, Juliet Bailey, David B. Cunningham, William F. Dove, Patterns of inheritance, development and the mitotic cycle in the protist Physarum polycephalum web science. ,vol. 35, pp. 1- 69 ,(1993) , 10.1016/S0065-2911(08)60096-X
R. J. Inglis, H. R. Matthews, E. M. Bradbury, The Molecular Basis for the Control of Cell Division Springer, Berlin, Heidelberg. pp. 240- 248 ,(1976) , 10.1007/978-3-642-66455-7_30
Gerard Pierron, Temporal Order of Replication and Gene Expression in Physarum polycephalum Springer New York. pp. 67- 77 ,(1986) , 10.1007/978-1-4613-2203-0_4
W. Sachsenmaier, K. Hansen, LONG- AND SHORT-PERIOD OSCILLATIONS IN A MYXOMYCETE WITH SYNCHRONOUS NUCLEAR DIVISIONS**Supported by the “Deutsche Forschungsgemeinschaft”. Biological and Biochemical Oscillators. pp. 429- 447 ,(1973) , 10.1016/B978-0-12-167872-2.50038-8
R. Mahendran, M.S. Spottswood, A. Ghate, M.L. Ling, K. Jeng, D.L. Miller, Editing of the mitochondrial small subunit rRNA in Physarum polycephalum. The EMBO Journal. ,vol. 13, pp. 232- 240 ,(1994) , 10.1002/J.1460-2075.1994.TB06253.X
Werner F. Nader, Gene Cloning and Construction of Genomic Libraries in Physarum Springer, Boston, MA. pp. 291- 300 ,(1986) , 10.1007/978-1-4613-2203-0_22