Can we trust tumour markers in pregnancy after breast cancer? A case of elevated CA 15-3 in the third trimester of pregnancy normalising after delivery.

作者: Barbara Buonomo , Stefania A Noli , Alessandra Santini , Carlo Alviggi , Fedro A Peccatori

DOI: 10.3332/ECANCER.2019.979

关键词:

摘要: We realized a narrative review of the current literature starting from case patient with raised CA15-3 during an uncomplicated pregnancy after breast cancer. The aim our paper was to assess specificity, physiological changes and clinical utility CA 15-3 monitoring cancer, practice retrieving most relevant evidence in literature.

参考文章(24)
R Kokko, K Holli, M Hakama, Ca 15-3 in the follow-up of localised breast cancer: a prospective study European Journal of Cancer. ,vol. 38, pp. 1189- 1193 ,(2002) , 10.1016/S0959-8049(01)00429-4
F. Akinlade, N. J. Cowans, M. C. Kisanga, K. Spencer, Maternal serum CA 19-9 and CA 15-3 levels in pregnancies affected by trisomy 21. Prenatal Diagnosis. ,vol. 32, pp. 644- 648 ,(2012) , 10.1002/PD.3875
Marie-Hélène Schlageter, Jérôme Larghero, Bruno Cassinat, Marie-Elisabeth Toubert, Caroline Borschneck, Jean-Didier Rain, Serum Carcinoembryonic Antigen, Cancer Antigen 125, Cancer Antigen 15-3, Squamous Cell Carcinoma, and Tumor-associated Trypsin Inhibitor Concentrations during Healthy Pregnancy Clinical Chemistry. ,vol. 44, pp. 1995- 1998 ,(1998) , 10.1093/CLINCHEM/44.9.1995
Ralph J. Lellé, Eberhard Henkel, Dieter Leinemann, Klaus Goeschen, Measurement of CEA, TPA, neopterin, CA125, CA153 and CA199 in sera of pregnant women, umbilical cord blood and amniotic fluid. Gynecologic and Obstetric Investigation. ,vol. 27, pp. 137- 142 ,(1989) , 10.1159/000293641
Angeliki Sarandakou, Efthimia Protonotariou, Demetrios Rizos, Tumor markers in biological fluids associated with pregnancy. Critical Reviews in Clinical Laboratory Sciences. ,vol. 44, pp. 151- 178 ,(2007) , 10.1080/10408360601003143
H. Schröcksnadel, G. Daxenbichler, E. Artner, G. Steckel-Berger, O. Dapunt, Tumor markers in hypertensive disorders of pregnancy. Gynecologic and Obstetric Investigation. ,vol. 35, pp. 204- 208 ,(1993) , 10.1159/000292701
Sileny N Han, Anouk Lotgerink, Mina Mhallem Gziri, Kristel Van Calsteren, Myriam Hanssens, Frédéric Amant, Physiologic variations of serum tumor markers in gynecological malignancies during pregnancy: a systematic review BMC Medicine. ,vol. 10, pp. 86- 86 ,(2012) , 10.1186/1741-7015-10-86
Şerif Ercan, Özge Kaymaz, Nihal Yücel, Asuman Orçun, Serum concentrations of CA 125, CA 15-3, CA 19-9 and CEA in normal pregnancy: a longitudinal study Archives of Gynecology and Obstetrics. ,vol. 285, pp. 579- 584 ,(2012) , 10.1007/S00404-011-2025-4
Jai B. Sharma, Subhadra Sharma, B.R. Usha, Ashish Gupta, Sunesh Kumar, Asok K. Mukhopadhyay, A cross-sectional study of tumor markers during normal and high-risk pregnancies. International Journal of Gynecology & Obstetrics. ,vol. 129, pp. 203- 206 ,(2015) , 10.1016/J.IJGO.2014.12.014