Fármacos antiangiogénicos en enfermedades neovasculares de la retina

作者: Gabriela Belén Maldonado Montoya , Guillermo Vinicio Arellano Barriga , Sami Imasumak Mendoza Pilco , Cristian Alonso Moncayo Yauripoma , Jorge Leonardo Peralvo Alulema

DOI: 10.51581/RCCM.V20I1.156

关键词:

摘要: An Increased vascular endothelial growth factor in degenerative, obstructive and even neoplastic processes is the main pathophysiological mechanism for formation of aberrant blood vessels, which are detrimental put at risk visual acuity individual. In recent years, creation antiangiogenic (anti-VEGF) drugs their intravitreal use have revolutionized therapy retinal neovascular diseases provided an increase quality life people suffering from it. The following narrative review article seeks to analyze safety, efficacy, posology, route administration international regimens anti-VEGF treatment Exudative Age- Associated Macular Degeneration (AMD), Diabetic Oedema (DME), Occlusion Central Retina Vein (CRVO), Retinal Venous Branch (BRVO) Retinoblastoma. intraocular represents a safe effective choice pathologies.

参考文章(7)
Usha Reddy, Magdalena Krzystolik, Antiangiogenic therapy with interferon alfa for neovascular age‐related macular degeneration Cochrane Database of Systematic Reviews. ,(2006) , 10.1002/14651858.CD005138.PUB2
Vikas Tah, Harry O. Orlans, Jonathan Hyer, Edward Casswell, Nizar Din, Vishnu Sri Shanmuganathan, Louise Ramskold, Saruban Pasu, Anti-VEGF Therapy and the Retina: An Update Journal of Ophthalmology. ,vol. 2015, pp. 627674- 627674 ,(2015) , 10.1155/2015/627674
Gianni Virgili, Mariacristina Parravano, Francesca Menchini, Jennifer R Evans, Anti‐vascular endothelial growth factor for diabetic macular oedema Cochrane Database of Systematic Reviews. ,vol. 10, ,(2014) , 10.1002/14651858.CD007419.PUB4
Virgilio Morales-Cantón, José Luis Guerrero-Naranjo, Raúl Vélez-Montoya, Jans Fromow-Guerra, Hugo Quiroz-Mercado, Daniel Moreno-Páramo, Terapia antiangiogénica ocular: experiencia clínica en México Gaceta Medica De Mexico. ,vol. 144, pp. 245- 253 ,(2008)
Gordon C Jayson, Robert Kerbel, Lee M Ellis, Adrian L Harris, Antiangiogenic therapy in oncology: current status and future directions. The Lancet. ,vol. 388, pp. 518- 529 ,(2016) , 10.1016/S0140-6736(15)01088-0
João Rafael de Oliveira Dias, Gabriel Costa de Andrade, Eduardo Amorim Novais, Michel Eid Farah, Eduardo Büchele Rodrigues, None, Fusion proteins for treatment of retinal diseases: aflibercept, ziv-aflibercept, and conbercept International Journal of Retina and Vitreous. ,vol. 2, pp. 3- 3 ,(2016) , 10.1186/S40942-016-0026-Y
Dong Yoon Kim, Jeong A Choi, Jae-Young Koh, Young Hee Yoon, Efficacy and safety of aflibercept in in vitro and in vivo models of retinoblastoma Journal of Experimental & Clinical Cancer Research. ,vol. 35, pp. 171- 171 ,(2016) , 10.1186/S13046-016-0451-7