Lipopolysaccharide induces alterations in ovaries and serum level of progesterone and 17β-estradiol in the mouse

摘要: Our objective was to investigate the effect of gram-negative bacterial infection on ovaries and serum level P4 17β-E2 during preimplantation days pregnancy in mouse. We found that lipopolysaccharide alters the serum E2 elevates E2/P4 ratio, which may keep uterus nonreceptive also not prepare developing blastocysts for implantation A large infiltration macrophages corpora lutea appearance graafian follicles from day 3.5 because treatment, reflect a infection, be responsible ovarian dysfunction altered serum.