Sensitive and selective detection of zinc ions in neuronal vesicles using PYDPY1, a simple turn-on dipyrrin
作者： Yujiang Mei , Christopher J. Frederickson , Leonard J. Giblin , John H. Weiss , Yuliya Medvedeva
DOI: 10.1039/C1CC12181B
关键词:
摘要: A new class of in vitroZn(II) chemosensor based on dipyrrin has been developed. 5-(Pyren-1-yl)-4,6-dipyrrin (PYDPY1) was synthesized and exhibited high selectivity sensitivity to Zn(II) (Kd 20 μM) compared other metal ions. PYDPY1 applied the visualization concentration hippocampal tissue.
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sci-hub.se 参考文章(22)
Tomoya Hirano, Kazuya Kikuchi, Yasuteru Urano, Tsunehiko Higuchi, Tetsuo Nagano, Novel Zinc Fluorescent Probes Excitable with Visible Light for Biological Applications Angewandte Chemie International Edition. ,vol. 39, pp. 1052- 1054 ,(2000) , 10.1002/(SICI)1521-3773(20000317)39:6<1052::AID-ANIE1052>3.0.CO;2-5
P D Zalewski, I J Forbes, W H Betts, Correlation of apoptosis with change in intracellular labile Zn(II) using zinquin [(2-methyl-8-p-toluenesulphonamido-6-quinolyloxy)acetic acid], a new specific fluorescent probe for Zn(II) Biochemical Journal. ,vol. 296, pp. 403- 408 ,(1993) , 10.1042/BJ2960403
Elizabeth M. Nolan, Jacek Jaworski, Ken-Ichi Okamoto, Yasunori Hayashi, Morgan Sheng, Stephen J. Lippard, QZ1 and QZ2: Rapid, Reversible Quinoline-Derivatized Fluoresceins for Sensing Biological Zn(II) Journal of the American Chemical Society. ,vol. 127, pp. 16812- 16823 ,(2005) , 10.1021/JA052184T
C.J. Frederickson, E.J. Kasarskis, D. Ringo, R.E. Frederickson, A quinoline fluorescence method for visualizing and assaying the histochemically reactive zinc (bouton zinc) in the brain. Journal of Neuroscience Methods. ,vol. 20, pp. 91- 103 ,(1987) , 10.1016/0165-0270(87)90042-2
Christopher J Chang, Elizabeth M Nolan, Jacek Jaworski, Shawn C Burdette, Morgan Sheng, Stephen J Lippard, Bright Fluorescent Chemosensor Platforms for Imaging Endogenous Pools of Neuronal Zinc Chemistry & Biology. ,vol. 11, pp. 203- 210 ,(2004) , 10.1016/J.CHEMBIOL.2004.01.017
C.J. Frederickson, B.A. Rampy, S. Reamy-Rampy, G.A. Howell, Distribution of histochemically reactive zinc in the forebrain of the rat Journal of Chemical Neuroanatomy. ,vol. 5, pp. 521- 530 ,(1992) , 10.1016/0891-0618(92)90007-D
Pengju Jiang, Zijian Guo, Fluorescent detection of zinc in biological systems: recent development on the design of chemosensors and biosensors Coordination Chemistry Reviews. ,vol. 248, pp. 205- 229 ,(2004) , 10.1016/J.CCT.2003.10.013
Chang-Hee Lee, Jonathan S. Lindsey, One-flask synthesis of meso-substituted dipyrromethanes and their application in the synthesis of trans-substituted porphyrin building blocks Tetrahedron. ,vol. 50, pp. 11427- 11440 ,(1994) , 10.1016/S0040-4020(01)89282-6
Yujiang Mei, Paul A. Bentley, A ratiometric fluorescent sensor for Zn2+ based on internal charge transfer (ICT) Bioorganic & Medicinal Chemistry Letters. ,vol. 16, pp. 3131- 3134 ,(2006) , 10.1016/J.BMCL.2006.03.058
Nathaniel C. Lim, Jolene V. Schuster, Maura C. Porto, Maria A. Tanudra, Lili Yao, Hedley C. Freake, Christian Brückner, Coumarin-based chemosensors for zinc(II): toward the determination of the design algorithm for CHEF-type and ratiometric probes. Inorganic Chemistry. ,vol. 44, pp. 2018- 2030 ,(2005) , 10.1021/IC048905R