Effect of adenine on bacterial translocation using technetium-99m labeled E . coli in an intestinal obstruction model in rats
作者： Uğur Oflaz , Fatma Yurt Lambrecht , Osman Yilmaz , Çetin Pekçetin
DOI: 10.1007/S10967-012-2223-Y
关键词:
摘要: This study aims to investigate effects of adenine on bacterial translocation (BT) using 99mTc-labeled E. coli in an intestinal obstruction rat model. In the twenty-one rats were used. The divided into three groups according different feeding patterns. control group (CG) was fed with a standard chow diet for 7 days. Group A1 and A2 supplemented At end period, after all submitted obstruction. 99mTc-E. injected rats’ terminal ileum under anesthetic. sacrificed aseptic conditions at 24th h surgery. uptake determined organs such as liver, mesenteric lymph nodes, spleen ileum. results show that decreased blood comparing CG. As result, it observed reduced level BT when compared beneficial effect observed. However, further studies are needed more clearly assess how this benefit can be achieved.
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M. GATT, B. S. REDDY, J. MACFIE, Review article: bacterial translocation in the critically ill--evidence and methods of prevention. Alimentary Pharmacology & Therapeutics. ,vol. 25, pp. 741- 757 ,(2006) , 10.1111/J.1365-2036.2006.03174.X
Rosana das Graças Carvalho dos Santos, Mirelle Lomar Viana, Simone Vasconcelos Generoso, Rosa Esteves Arantes, Maria Isabel Toulson Davisson Correia, Valbert Nascimento Cardoso, Glutamine Supplementation Decreases Intestinal Permeability and Preserves Gut Mucosa Integrity in an Experimental Mouse Model Journal of Parenteral and Enteral Nutrition. ,vol. 34, pp. 408- 413 ,(2010) , 10.1177/0148607110362530
Simone Odília Fernandes Diniz, Alfredo José Afonso Barbosa, Ivana Durval Araújo, David Lee Nelson, Leonardo Augusto da Silva Machado, Mário Bernardo Filho, Valbert Nascimento Cardoso, Assessment of Bacterial Translocation in Obstructive Jaundice Using Tc-99m Escherichia coli Brazilian Archives of Biology and Technology. ,vol. 48, pp. 45- 49 ,(2005) , 10.1590/S1516-89132005000700006
D. Nicholas Ragsdale, Kenneth G. Proctor, Acadesine and intestinal barrier function after hemorrhagic shock and resuscitation. Critical Care Medicine. ,vol. 28, pp. 3876- 3884 ,(2000) , 10.1097/00003246-200012000-00023
Luca Gianotti, J. Wesley Alexander, Tonyia Pyles, Ryoji Fukushima, Arginine-supplemented diets improve survival in gut-derived sepsis and peritonitis by modulating bacterial clearance. The role of nitric oxide. Annals of Surgery. ,vol. 217, pp. 644- 654 ,(1993) , 10.1097/00000658-199306000-00006
Akin Aydogan, Kemal Kismet, Bulent Kilicoglu, Serap Erel, Ali Haldun Ozcan, Avni Gollu, Eda Yildiz, Mehmet Ali Akkus, None, Effects of various enteral nutrition solutions on bacterial translocation and intestinal morphology during the postoperative period. Advances in Therapy. ,vol. 24, pp. 41- 49 ,(2007) , 10.1007/BF02849991
Arved Weimann, Leonard Bastian, Werner E. Bischoff, Martin Grotz, Matthias Hansel, Joachim Lotz, Christian Trautwein, Günter Tusch, Hans J. Schlitt, Gerd Regel, Influence of arginine, omega-3 fatty acids and nucleotide-supplemented enteral support on systemic inflammatory response syndrome and multiple organ failure in patients after severe trauma Nutrition. ,vol. 14, pp. 165- 172 ,(1998) , 10.1016/S0899-9007(97)00429-2
Mirelle L. Viana, Rosana G.C. Santos, Simone V. Generoso, Rosa M.E. Arantes, Maria Isabel T.D. Correia, Valbert N. Cardoso, Pretreatment with arginine preserves intestinal barrier integrity and reduces bacterial translocation in mice. Nutrition. ,vol. 26, pp. 218- 223 ,(2010) , 10.1016/J.NUT.2009.04.005
S.O.F Diniz, B.M Resende, E.A Nunan, C.J.R Simal, V.N Cardoso, 99mTechnetium labelled Escherichia coli. Applied Radiation and Isotopes. ,vol. 51, pp. 33- 36 ,(1999) , 10.1016/S0969-8043(98)00185-7
Reiner Wiest, Heiko C Rath, Bacterial translocation in the gut Best Practice & Research in Clinical Gastroenterology. ,vol. 17, pp. 397- 425 ,(2003) , 10.1016/S1521-6918(03)00024-6